Dramatic structural changes resulting from the loss of a crucial hydrogen bond in the hinge region involved in C- terminal helix swapping in SurE: a survival protein from Salmonella typhimurium.
Mathiharan YK, Pappachan A, H. S. Savithri, M. R. N. Murthy
Biochemical characterization of C4 protein of Cotton Leaf Curl Kokhran Virus-Dabawali.
Guha D, Poornima Priyadarshini CG, Purakayastha A, Thippeswamy R, Lakshmikanth M, H.S. Savithri
Biochim Biophys Acta
Mechanistic features of Salmonella typhimurium propionate kinase (TdcD): Insights from kinetic and crystallographic studies.
Chittori S, Simanshu DK, Banerjee S, Murthy AM, Mathivanan S, H. S. Savithri, M. R. N. Murthy
Biochim Biophys Acta
Identification of key amino acid residues in the catalytic mechanism of diaminopropionate ammonialyase (DAPAL) from S. typhimurium.
Kalyani JN, Bisht S, Lakshmikanth M, M. R. N. Murthy, H. S. Savithri
N-terminal disordered domain of Saccharomyces cerevisiae Hop1 protein is dispensable for DNA binding, bridging, and synapsis of double-stranded DNA molecules but is necessary for spore formation.
Khan, K., Vipin, Madhavan, T. P., Kshirsagar, R., Boosi, K. N., Sadhale, P. and Muniyappa, K.
Patterns of variation at diabetes and obesity associated loci may mirror neutral patterns of human population diversity and diabetes prevalence in India.
Raj, S. M., Prakash, P. H., Kadandale, J., Lahr, M. M., Gallego Romero, I., Yadhav, J., Iliescu, F. M., Rai, N., Crivellaro, F., Chaubey, G., Villems, R., Thangaraj K., Muniyappa, K, Chandra, H. S., and Kivisild, T.
Ann. Hum. Genet
Processing of DNA double-strand breaks and inter- mediates of recombination and repair by Saccharomyces cerevisiae Mre11 and its stimulation by Rad50, Xrs2 and Sae2 proteins
Ghodke, I., and Muniyappa, K.
J. Biol. Chem
Evidence for the role for Mycobacterium tuberculosis RecG helicase in DNA repair and recombination.
Thakur, R. S., Basavaraju, S., Somyajit, K., Subramanya, S., Muniyappa, K., and Nagaraju, G.
Dynamics and regulation of RecA polymerization and de-polymerization on double-stranded DNA
Fu, H., Le, S. & Muniyappa, K. and Yan, J.
Force and ATP hydrolysis dependent regulation of RecA nucleoprotein filament by single-stranded DNA binding protein.
Fu, X., Le, S., Chen, H., Muniyappa, K. and Yan, J.
Nucl. Acids Res
Helicobacter pylori DprA alleviates restriction barrier for incoming DNA
Gajendradhar R. Dwivedi,
Desirazu N. Rao
Nucleic Acid Research
Inhibition of cancer cell proliferation and apoptosis-inducing activity of fungal taxol and its precursor baccatin III purified from endophytic Fusariumsolani.:
Chakravarthi, B.V.S.K, Sujay, R., Kuriakose, G.C., Karande, A.A., and Jayabaskaran, C.
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Thrombin-Inhibitory activity of aqueous leaf and flower extract of Catharanthus roseus.
Kuriakose, G.C., Krishna, T.H.A., Gudde, R.S., Jayabaskaran, C., and Surin, W.R.,
International Journal of General Medicine and Pharmacy
Naphthalene Carbohydrazone Based Dizinc(II) Chemosensor for a Pyrophosphate Ion and Its DNA Assessment Application in Polymerase Chain Reaction Products.:
Anbu, S., Kamalraj, S., Jayabaskaran, C., and Mukherjee P. S
Liquid chromatography-mass spectrometry based profile of bioactive compounds of Cucumiscallosus
Soama, P.S., Singha, T., Vijayvergiaa, R., and Jayabaskaran, C
Euro J Exp Bio
Photocytotoxic ferrocene-appended (L-tyrosine)-copper(II) complexes of
Goswami, T.K., Gadadhar S., Karande A.A. and Chakravarty A.K.
Photocytotoxicity of copper(II) complexes of curcumin and N-ferrocenylmethyl-L- amino acids
Goswami, T.K., Gadadhar, S., Gole, B., Karande, A.A., Chakravarty, A.R.
Eur J Med Chem
Characterization of monoclonal antibodies to Hepatitits C virus E2 glycoprotein which inhibit Hepatitis C virus-like particle binding to target cells.
Das S, Shetty KR, Kumar A, Radhika NS, Ranjitha T, Giriprakash C, Mukherjee A, Das S, Shaila MS Karande AA
Mapping the apoptosis inducing domain of an unomodulatory protein: glycodelin A.
Ponnalagu, D. and Karande A.A
Mol Cell Biochem.
Novel trafficking pathway of a type II RIP, abrin, and its A chain immunotoxin.
Gadadhar, S. and Karande A.A.
Mechanistic insights on neutralization of cytotoxic abrin by the mAb D6F10.
Bagaria, S., Bisht, S., Ponnalagu, D. and Karande A.A
DNA and protein targeting 1,2,4-triazole based water soluble dinickel(II) complexes enhances antiproliferation and lactate dehydrogenase inhibition..
Poornima, S., Anbu, S., Ravishankaran, R., Sundarmoorthy, S., Vennila, K.N., Karande A.A., Velmurugan, D., Kandaswamy, M.
Inhibition of cancer cell proliferation and apoptosis-inducing activity of fungal taxol and Its precursor baccatin III purified from endophytic Fusarium solani.
Chakravarthi, B.V.S.K., Sujay, R., Kuriakose, G.C., Karande, A.A. & Jayabaskaran, C.
Cancer Cell International
Malaria parasite-synthesized heme is essential in the mosquito and liver stages and complements host heme in the blood stages of infection.
Nagaraj VA, Sundaram B, Varadarajan NM, Subramani PA, Kalappa DM, Ghosh SK, Padmanaban G
Pre-clinical toxicity & immunobiological evaluation of DNA rabies vaccine & combination rabies vaccine in rhesus monkeys (Macaca mulatta).
Dinesh Kumar, B., Uday Kumar, P., Prasanna Krishna, T., Kalyanasundaram, S., Suresh, P., Jagadeesan, V., Hariharan, S., Nadamuni Naidu, A., Kamala Krishnaswamy, Rangarajan, P. N., Srinivasan, V. A., Reddy, G. S., and Sesikeran, B
Indian Journal of Medical Research
A soluble diacy glycerolacyl transferase is involved in triacylglycerol biosynthesis in the oleaginous yeast Rhodotorulaglutinis.
Rani SH, Saha S, Rajasekharan R
Identification of an exported heat shock protein 70 in Plasmodium falciparum
Grover M, Chaubey S, Ranade S, Tatu U
The bystander effect in optically trapped red blood cells due to Plasmodium falciparum infection.
Paul A, Pallavi R, Tatu US, Natarajan V.
Transactions of the Royal Society of Tropical Medicine and Hygiene
Identification of immuno-dominant antigens of Trypanosoma evansi for detection of chronic trypanosomosis using experimentally infected equines.
Yadav SC, Kumar R, Kumar V, Jaideep, Kumar R, Gupta AK, Bera BC, Tatu U
Research in veterinary science
Regulation of chemokines, CCL3 and CCL4, by Interferon-gamma and Nitric oxide synthase 2 in mouse macrophages and during Salmonella enterica Serovar Typhimurium infection.
B.Chandrasekar,M. Deobagkar-Lele, E. S. Victor and D. Nandi
Journal of Infectious Diseases
Interferon-gamma and glucocorticoid mediated pathways synergize to enhance death of CD4+CD8+ thymocytes during Salmonella enterica serovar Typhimurium infection
M. Deobagkar-Lele, S. Chacko E. Victor, J. Kadthur and D. Nandi
Catalytic activity of Peptidase N is required for adaptation of Escherichia coli to nutritional downshift and high temperature stress
M. Bhosale, A. Kumar, M. Das, C. Bhaskarla, V. Agarwal and D. Nandi
Type IA topoisomerase inhibition by clamp closure.
Leelaram MN, Bhat AG, Godbole AA, Bhat RS, Manjunath R, Nagaraja V
Infection of human endothelial cells by Japanese encephalitis virus: Increased expression and release of soluble HLA-E
Shwetank, Date OS, Kim KS, Manjunath R.
A multi-level multi-scale approach to study essential genes in Mycobacterium tuberculosis
Ghosh, S., Baloni, P., Mukherjee, S., Anand, A., and Chandra, N.
BMC Systems Biology
Weighting schemes in metabolic graphs for identifying biochemical routes
Ghosh, S., Baloni, P., Vishveshwara, S., and Chandra, N.
Syst Synth Biol
Mining large-scale response networks reveals ‘topmost activities’ in Mycobacterium tuberculosis infection
Sambarey, A., Prashanthi, K. & Chandra, N
Nature Scientific Reports
Current trends in modeling host–pathogen interactions
Mukherjee S., Sambarey A., Prashanthi K. and Chandra N.
WIREs Data Mining and Knowledge Discovery
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Rationalization and prediction of drug resistant mutations in targets for clinical anti-tubercular drugs
Padiadpu J, Mukherjee S, Chandra N
J Biomol Struct Dyn
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Network approaches to drug discovery
N. Chandra and J. Padiadpu
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G-quadruplex Structures Formed at the HOX11 Breakpoint Region Contribute to its Fragility during t(10;14) Translocation in T-cell Leukemia.
Mridula Nambiar, Mrinal Srivastava, Vidya Gopalakrishnan, Sritha K. Sankaran and Sathees C. Raghavan
Mol Cell Biol
Propyl-2-(8-(3,4-difluorobenzyl)-2',5'-dioxo-8-azaspiro[bicyclo[3.2.1] octane-3,4'-imidazolidine]-1'-yl) acetate induces apoptosis in human leukemia cells through mitochondrial pathway following cell cycle arrest, ,:
Chandagirikoppal V. Kavitha, Mridula Nambiar, Pavan B. Narayanaswamy, Elizabeth Thomas, Ujjwal Rathore, Bibha Choudhary, Kanchugarakoppal S. Rangappa, and Sathees C. Raghavan
Targeted Cancer Therapy: The Role of BCL2 Inhibitors” Editor J. N. Govil. In “Recent Developments in Biotechnology” (1st Edition)
Divyaanka Iyer and Sathees C. Raghavan
8-methoxypyrimido [4’,5’:4,5]thieno(2,3-b) quinoline-4(3H)one, a newer anticancer drug induces neuro 2a neuroblastoma cell death through p53-dependent, caspase-dependent and -independent apoptotic pathways,:
Upasana Sahu, Gopal M. Advirao, Sathees C. Raghavan and Ranjit Giri
A novel DNA intercalator, 8-Methoxy pyrimido [4’,5’:4,5]thieno (2,3-b)quinoline -4(3H)-one induces apoptosis in cancer cells, inhibits the tumor progression and enhances lifespan of mice.
Sheetal Sharma, Kuppusamy Panjamurthy, Bibha Choudhary, Shahabuddin M.S., Gopal M. Advirao and Sathees C. Raghavan
Chromosomal Translocations among the Healthy Human Population: Implications in Oncogenesis.
Mridula Nambiar and Sathees C. Raghavan
Cell. Mol. Life Sci.
Synthesis and evaluation of 2,5-di(4-aryloylaryloxymethyl)-1,3,4-oxadiazoles as
Gurupadaswamy HD, Girish V, Kavitha CV, Sathees C. Raghavan Khanum SA.
Eur. J. Med. Chem.
Rapid Characterization of Hydrogen Exchange in Proteins,
Thakur A, Kousik Chandra K, Abhinav Dubey A, D’Silva P* and Atreya H.S*.
Angew. Chem. Int. Ed.,
Molecular insights revealing interaction of Tim23 and channel subunits of presequence translocase.
Pareek G, Krishnamoorthy V, D'Silva P.
Mol. Cell. Biol.
Enhancing the photocytotoxic potential of curcumin on terpyridyl lanthanide (iii) complex formation.
Hussain A, Somyajit K, Banik B, Banerjee S, Nagaraju G, Chakravarty AR
ATM- and ATR-mediated phosphorylation of XRCC3 regulates DNA double strand break-induced checkpoint activation and repair
Somyajit, K., Basavaraju, S., Scully, R. and Nagaraju, G
Mol. Cell Biol.
Evidence for the role of Mycobacterium tuberculosis RecG helicase in DNA repair and recombination.
Thakur, R.S, Basavaraju, S., Somyajit, K., Subramanya, S., Muniyappa, K. and Nagaraju, G.
Photoactivated DNA cleavage and anticancer activity of oxovanadium(IV) complexes of
Balaji, B., Somyajit, K., Banik, B., Nagaraju, G., and Chakravarty, A.R
Inorganica Chimica Acta